Week 6 College Football Predictions 2012
| Game | Straight up Winner | Against the Line Winner |
| Thursday October 4th | ||
| East Carolina Pirates +14 @ Central Florida Golden Knight -14 | Central Florida Golden Knights | East Carolina Pirates |
| USC Trojans -12.5 @ Utah +12.5 | USC Trojans | USC Trojans |
| Arkansas State Red Wolves +1.5 @ Florida International Golden Panthers -1.5 | Arkansas State Red Wolves | Arkansas State Red Wolves |
| Friday Ocotber 5 | ||
| Pittsburgh Panthers -3 @ Syracuse Orange +3 | Pittsburgh Panthers | Pittsburgh Panthers |
| Utah St. Aggies @ BYU Cougars | BYU Cougars | OTB |
| Saturday October 6 | ||
| Navy Midshipmen +10.5 @ Air Force Falcons -10.5 | Air Force Falcons | Air force Falcons |
| Michigan State Spartans -14.5 @ Indiana Hoosiers +14.5 | Michigan State Spartans | Michigan State Spartans |
| Northern Illinois Huskies -2.5 @ Ball State Cardinals +2.5 | Northern Illinois Huskies | Northern Illinois Huskies |
| Boston College Eagles -9.5 @ Army Black Knights +9.5 | Boston College Eagles | Boston College Eagles |
| Bowling Green Falcons -5 @ Akron Zips +5 | Bowling Green Falcons | Bowling Green Flacons |
| Miami Redhawks +21 @ Cincinnati Bearcats -21 | Cincinnati Bearcats | Cincinnati Bearcats |
| Georgia Tech Yellow Jackets +10 @ Clemson Tigers -10 | Clemson Tigers | Clemson Tigers |
| Virginia Cavaliers @ Duke Blue Devils | Virginia Cavaliers | OTB |
| South Florida Bulls -5 @ Temple Owls +5 | South Florida Bulls | South Florida Bulls |
| Northwestern Wildcats +3.5 @ Penn State Nittany Lions -3.5 | Penn State | Northwestern Wildcats |
| Kent State Golden Flash +3.5 @ Eastern Michigan -3.5 | Kent State Golden Flash | Kent State Golden Flash |
| UConn Huskies +9.5 @ Rutgers Scarlet Knights -9.5 | Rutgers Scarlet Knight | Rutgers Scarlet Knights |
| Massachusetts Minutemen +15 @ western Michigan Broncos -15 | Western Michigan Broncos | Western Michigan Broncos |
| Vanderbilt Commodores +7.5 @ Missouri tigers -7.5 | Missouri Tigers | Missouri Tigers |
| Texas A&M Aggies -9.5 @ Ole Miss Rebels +9.5 | Texas A&M Aggies | Texas A&M Aggies |
| Virginia Tech Hokies +3.5 @ North Carolina Tar Heels -3.5 | North Carolina Tar Heels | North Carolina Tar Heels |
| Washington Huskies +24.5 @ Oregon Ducks -24.5 | Oregon Ducks | Washington Huskies |
| Georgia Bulldogs +3 @ South Carolina Gamecocks -3 | Georgia Bulldogs | Georgia Bulldogs |
| West Virginia Mountaineers +6.5 @ Texas Longhorns -6.5 | West Virginia Mountaineers | West Virginia Mountaineers |
| Iowa State Cyclones +12 @ TCU Horned Frogs -12 | TCU Horned Frogs | TCU Horned Frogs |
| Illinois Fighting Illini +14.5 @ Wisconsin Badgers -14.5 | Wisconsin Badgers | Wisconsin Badgers |
| Kansas Jayhawks +24.5 @ Kansas State Wildcats -24.5 | Kansas State Wildcats | Kansas State Wildcats |
| UCLA Bruins -2.5 @ Cal Golden Bears +2.5 | UCLA Bruins | UCLA Bruins |
| Arkansas Razorbacks +10 @ Auburn tigers -10 | Arkansas Razorbacks | Arkansas Razorbacks |
| Michigan Wolverines -3.5 @ Purdue Boilermakers +3.5 | Purdue Boilermakers | Purdue Boilermakers |
| Wyoming Cowboys +15.5 @ Nevada Wolf Pack -15.5 | Nevada Wolf Pack | Wyoming Cowboys |
| New Mexico State Aggies +9.5 @ Idaho Vandals -9.5 | Idaho Vandals | New Mexico State Aggies |
| Arizona Wildcats +11.5 @ Stanford Cardinal -11.5 | Stanford Cardinal | Arizona Wildcats |
| Oklahoma Sooners -5 @ Texas Tech Red Raiders +5 | Oklahoma Sooners | Oklahoma Sooners |
| Central Michigan Chippewas +13.5 @ Toledo Rockets -13.5 | Toledo Rockets | Toledo Rockets |
| Boise State Broncos -11 @ Southern Miss Golden Eagles +11 | Boise State Broncos | Boise State Broncos |
| Rice Owls @ Memphis Tigers | Rice Owls | OTB |
| Wake Forest Demon Deacons +4.5 @ Maryland Terrapins -4.5 | Maryland Terrapins | Wake Forest Demon Deacons |
| Mississippi State Bulldogs @ Kentucky Wildcats | Mississippi State Bulldogs | OTB |
| UNLV Runnin' Rebels +25 @ Louisiana Tech Bulldogs -25 | Louisiana Tech Bulldogs | UNLV Runnin' Rebels |
| Tulsa Golden Hurricane -4 @ Marshall Thundering Herd +4 | Marshall Thundering Herd | Marshall Thundering Herd |
| Miami Hurricanes +13 @ Notre Dame Fighting Irish -13 | Notre Dame Fighting Irish | Notre Dame Fighting Irish |
| Buffalo Bulls +16 @ Ohio Bobcats -16 | Ohio Bobcats | Buffalo Bulls |
| Nebraska Cornhuskers +5 @ Ohio State Buckeyes -5 | Ohio State Buckeyes | Ohio State Buckeyes |
| Hawaii Warriors +20 @ San Diego State Aztecs -20 | San Diego State Aztecs | San Diego State Aztecs |
| Fresno State Bulldogs -16 @ Colorado State Rams +16 | Fresno State Bulldogs | Fresno State Bulldogs |
| LSU Tigers -3.5 @ Florida Gators +3.5 | Florida Gators | Florida Gators |
| Texas State Bobcats +3 @ New Mexico Lobos -3 | Texas State Bobcats | Texas State Bobcats |
| SMU Mustangs +2.5 @ UTEP Miners -2.5 | SMU Mustangs | SMU Mustangs |
| Tulane Green Wave @ Louisiana Lafayette Ragin' Cajuns | Louisiana Lafayette Ragin' Cajuns | OTB |
| North Texas Mean Green +11 @ Houston Cougars -11 | Houston Cougars | Houston Cougars |